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Django is a high-level Python web framework that encourages rapid development and clean, pragmatic design. Built by experienced developers, Django takes care of much of the hassle of web development, allowing developers to focus on writing their apps without needing to reinvent the wheel. It follows the model-template-view (MTV) architectural pattern, which is similar to MVC. Django is known for its "batteries included" philosophy, providing a comprehensive set of tools and features out of the box, including an ORM, authentication system, admin interface, and more.

CodeIgniter is a powerful PHP framework with a very small footprint, built for developers who need a simple and elegant toolkit to create full-featured web applications. It follows the MVC (Model-View-Controller) pattern and is known for its speed, simplicity, and strong performance. CodeIgniter comes with a rich set of libraries for commonly needed tasks, along with a simple interface and logical structure to access these libraries. It's designed to be flexible, allowing developers to work in a way that suits their coding style.

Neos Flow (formerly TYPO3 Flow) is a powerful PHP web application framework designed for creating scalable and robust applications. It follows modern development principles like domain-driven design, command query responsibility segregation, and aspect-oriented programming. Flow provides a comprehensive set of features including dependency injection, a powerful object-relational mapper, and a flexible MVC architecture. It's particularly well-suited for complex, enterprise-level applications and serves as the foundation for the Neos Content Management System.

Play Framework is an open-source web application framework written in Scala and Java which follows the model-view-controller (MVC) architectural pattern. It aims to optimize developer productivity by using convention over configuration, hot code reloading, and display of errors in the browser. Play supports asynchronous programming patterns, making it suitable for building scalable, reactive applications. It integrates well with both Java and Scala ecosystems and provides features like built-in testing support, database access layers, and RESTful APIs out of the box.