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CakePHP is an open-source web framework that follows the model-view-controller (MVC) approach. It's written in PHP and is designed to make developing, deploying and maintaining applications simpler. CakePHP features built-in security tools for protection against SQL injection, cross-site scripting (XSS), cross-site request forgery (CSRF), and form tampering. It also provides a flexible database access layer and a powerful scaffolding system that can build both basic and complex applications quickly. CakePHP is known for its convention over configuration approach, which can significantly speed up the development process.

Django is a high-level Python web framework that encourages rapid development and clean, pragmatic design. Built by experienced developers, Django takes care of much of the hassle of web development, allowing developers to focus on writing their apps without needing to reinvent the wheel. It follows the model-template-view (MTV) architectural pattern, which is similar to MVC. Django is known for its "batteries included" philosophy, providing a comprehensive set of tools and features out of the box, including an ORM, authentication system, admin interface, and more.

Qwik is designed for the fastest possible page load time, by delivering pure HTML with near 0 JavaScript.

Neos Flow (formerly TYPO3 Flow) is a powerful PHP web application framework designed for creating scalable and robust applications. It follows modern development principles like domain-driven design, command query responsibility segregation, and aspect-oriented programming. Flow provides a comprehensive set of features including dependency injection, a powerful object-relational mapper, and a flexible MVC architecture. It's particularly well-suited for complex, enterprise-level applications and serves as the foundation for the Neos Content Management System.

Spring Framework is a comprehensive programming and configuration model for modern Java-based enterprise applications. It's applicable on any deployment platform and provides infrastructure support at the application level, allowing developers to focus on business logic. Spring's core features can be used by any Java application, but there are extensions for building web applications on top of the Java EE platform. Notable features include dependency injection, aspect-oriented programming, and simplified data access. Spring also offers additional projects that extend its capabilities to areas like security, cloud computing, and big data.